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49ers vs Giants Week 5 SNF Prediction

With the San Francisco offense struggling at a historical pace and with New Yorks defense starting to click, the Niners figure to have their hands full in the Sunday Night Football 49ers-Giants game.

NBC will have the national television broadcast for the 49ers-Giants SNF game at 8:30 p.m. Eastern from MetLife Stadium.

After a rough 0-2 start, where New York blew fourth-quarter leads at Dallas and at home against Atlanta, the Giants have rallied to win two straight entering the 49ers-Giants contest. New York won a TNF game against Washington, 32-21, before putting together its best performance of the season last Sunday, winning 24-10 at Buffalo.

Quarterback Eli Manning has been solid for the Giants in 2015, but definitely not spectacular. He has 976 yards throwing in four games with seven touchdowns and one interception. But even with somewhat pedestrian numbers on the season, Manning has had the Giants in position to win all four games.

New Yorks rushing defense continues to impress, and it seems to be getting stronger each week. Against a San Francisco rushing offense that has had difficulty having success on the ground, this matchup may be the key to the 49ers-Giants SNF contest. Opponents have only managed 279 yards rushing against the Giants in four games.

Solving the entire New York defense figures to be a significant challenge for the San Francisco offense in the 49ers-Giants contest. The 49ers (1-3) have had one of the NFLs least successful offenses to this point in the 2015 season, and last Sundays 17-3 loss at home to Green Bay was one of the franchises worst performances in recent memory. San Francisco managed only eight first downs against Green Bay and 196 total yards. San Francisco has been outscored 107-28 the last three games, all losses.

The 49ers and Giants have played each other 30 times in NFL history, and each team has won 15. And they have quite an extensive playoff history against each other, with the playoff series tied 4-4. Not surprisingly for an all-time series that has been so even over the years, the 49ers and Giants have split their last four, 10, and 14 meetings.

San Francisco won the 49ers-Giants game last season at MetLife Stadium, 16-10. Colin Kaepernick threw for 193 yards and one score for San Francisco, and he rushed for 24 yards. Manning threw for 280 yards against the San Francisco defense, but the 49ers secondary had no problem diagnosing Manning, coming up with five interceptions.